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1

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

Yazdanpanah, Benjamin, Wiegmann, Katja, Tchikov, Vladimir, Krut, Oleg, Pongratz, Carola, Schramm, Michael, Kleinridders, Andre, Wunderlich, Thomas, Kashkar, Hamid, Utermöhlen, Olaf

Journal:

Year:

2009

Language:

english

File:

PDF, 863 KB

english, 2009

2

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity

Jais, Alexander, Solas, Maite, Backes, Heiko, Chaurasia, Bhagirath, Kleinridders, André, Theurich, Sebastian, Mauer, Jan, Steculorum, Sophie M., Hampel, Brigitte, Goldau, Julia, Alber, Jens, Förster,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

3

Mitochondrial dynamics impairment leads to adipogenesis failure

Pedro Castro, José, Fernando, Raquel, Hugo, Martín, Nowotny, Kerstin, Jung, Tobias, Wardelmann, Kristina, Kleinridders, André, Grune, Tilman

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 49 KB

english, 2017

4

Reversible gene knockdown in mice using a tight, inducible shRNA expression system

Seibler, J., Kleinridders, A., Kuter-Luks, B., Niehaves, S., Bruning, J. C., Schwenk, F.

Journal:

Nucleic Acids Research

Year:

2007

Language:

english

File:

PDF, 391 KB

english, 2007

5

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

André Kleinridders, Dominik Schenten, A. Christine Könner, Bengt F. Belgardt, Jan Mauer, Tomoo Okamura, F. Thomas Wunderlich, Ruslan Medzhitov, Jens C. Brüning

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

6

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Gupta, M. K., Teo, A. K. K., Rao, T. N., Bhatt, S., Kleinridders, A., Shirakawa, J., Takatani, T., Hu, J., De Jesus, D. F., Windmueller, R., Wagers, A. J., Kulkarni, R. N.

Journal:

Stem Cells Translational Medicine

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

7

Low steady-state oxidative stress inhibits adipogenesis by altering mitochondrial dynamics and decreasing cellular respiration

Fernando, Raquel, Wardelmann, Kristina, Deubel, Stefanie, Kehm, Richard, Jung, Tobias, Mariotti, Marco, Vasilaki, Aphrodite, Gladyshev, Vadim N., Kleinridders, AndrÃ©, Grune, Tilman, Castro, JosÃ© Ped

Journal:

Year:

2020

Language:

english

File:

PDF, 1.72 MB

english, 2020

8

Secondary Consequences of β Cell Inexcitability: Identification and Prevention in a Murine Model of KATP-Induced Neonatal Diabetes Mellitus

Maria Sara Remedi, Harley T. Kurata, Alexis Scott, F. Thomas Wunderlich, Eva Rother, Andre Kleinridders, Ailing Tong, Jens C. Brüning, Joseph C. Koster, Colin G. Nichols

Journal:

Cell Metabolism

Year:

2009

Language:

english

File:

PDF, 1.68 MB

english, 2009

9

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

Kleinridders, Andre, Cai, Weikang, Cappellucci, Laura, Ghazarian, Armen, Collins, William R., Vienberg, Sara G., Pothos, Emmanuel N., Kahn, C. Ronald

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 966 KB

english, 2015

10

Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity

Jais, Alexander, Solas, Maite, Backes, Heiko, Chaurasia, Bhagirath, Kleinridders, André, Theurich, Sebastian, Mauer, Jan, Steculorum, Sophie M., Hampel, Brigitte, Goldau, Julia, Alber, Jens, Förster,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.99 MB

english, 2016

11

Deciphering brain insulin receptor and IGF1 receptor signalling

Kleinridders, André

Journal:

Journal of Neuroendocrinology

Year:

2016

Language:

english

File:

PDF, 940 KB

english, 2016

12

SIRT3 protects against palmitate-induced neuronal lipotoxicity

Alfine, Eugenia, Deubel, Stafanie, Würschum, Norina, Kleinridders, André

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

13

Insulin: Schützender Anpassungsmechanismus im Gehirn

Kleinridders, André

Journal:

Diabetologie und Stoffwechsel

Year:

2019

File:

PDF, 104 KB

2019

14

Interplay of Dietary Fatty Acids and Cholesterol Impacts Brain Mitochondria and Insulin Action

Schell, Mareike, Chudoba, Chantal, Leboucher, Antoine, Alfine, Eugenia, Flore, Tanina, Ritter, Katrin, Weiper, Katharina, Wernitz, Andreas, Henkel, Janin, Kleinridders, AndrÃ©

Journal:

Year:

2020

File:

PDF, 2.98 MB

2020

15

Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function

Boucher, Jeremie, Softic, Samir, El Ouaamari, Abdelfattah, Krumpoch, Megan T., Kleinridders, Andre, Kulkarni, Rohit N., O’Neill, Brian T., Kahn, C. Ronald

Journal:

Year:

2016

Language:

english

File:

PDF, 2.65 MB

english, 2016

16

Impact of Brain Insulin Signaling on Dopamine Function, Food Intake, Reward, and Emotional Behavior

Kleinridders, André, Pothos, Emmanuel N.

Journal:

Current Nutrition Reports

Year:

2019

Language:

english

File:

PDF, 484 KB

english, 2019

17

VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding

Spohn, Gabriele, Kleinridders, Andre, Wunderlich, F. Thomas, Watzka, Matthias, Zaucke, Frank, Blum-bach, Katrin, Geisen, Christof, Seifried, Erhard, Müller, Clemens, Paulsson, Mats, Brüning, Jens, Old

Journal:

Thrombosis and Haemostasis

Year:

2009

File:

PDF, 858 KB

2009

18

Cell autonomous requirement of neurofibromin (Nf1) for postnatal muscle hypertrophic growth and metabolic homeostasis

Wei, Xiaoyan, Franke, Julia, Ost, Mario, Wardelmann, Kristina, BÃ¶rno, Stefan, Timmermann, Bernd, Meierhofer, David, Kleinridders, Andre, Klaus, Susanne, Stricker, Sigmar

Journal:

Journal of Cachexia, Sarcopenia and Muscle

Year:

2020

File:

PDF, 37.67 MB

2020

19

Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation

Jing, E., O'Neill, B. T., Rardin, M. J., Kleinridders, A., Ilkeyeva, O. R., Ussar, S., Bain, J. R., Lee, K. Y., Verdin, E. M., Newgard, C. B., Gibson, B. W., Kahn, C. R.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.34 MB

english, 2013

20

Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activity

Vienberg, Sara Gry, Kleinridders, André, Suzuki, Ryo, Kahn, C. Ronald

Journal:

Molecular Metabolism

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

21

Novel Dysregulation of Mitochondria Impacts Brain Insulin Signaling

Kleinridders, André

Journal:

Free Radical Biology and Medicine

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

22

Mitochondrial Chaperones in the Brain: Safeguarding Brain Health and Metabolism?

Castro, José Pedro, Wardelmann, Kristina, Grune, Tilman, Kleinridders, André

Journal:

Frontiers in Endocrinology

Year:

2018

Language:

english

File:

PDF, 1.52 MB

english, 2018

23

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes

Ussar, S., Lee, K. Y., Dankel, S. N., Boucher, J., Haering, M.-F., Kleinridders, A., Thomou, T., Xue, R., Macotela, Y., Cypess, A. M., Tseng, Y.-H., Mellgren, G., Kahn, C. R.

Journal:

Science Translational Medicine

Year:

2014

Language:

english

File:

PDF, 676 KB

english, 2014

24

Regional differences in brain glucose metabolism determined by imaging mass spectrometry

Kleinridders, André, Ferris, Heather A., Reyzer, Michelle L., Rath, Michaela, Soto, Marion, Manier, M. Lisa, Spraggins, Jeffrey, Yang, Zhihong, Stanton, Robert C., Caprioli, Richard M., Kahn, C. Ronal

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 2.31 MB

english, 2018

25

SIRT3 overexpression in neurons enables β-oxidation and prevents palmitate-induced insulin resistance

Alfine, Eugenia, Wardelmann, Kristina, Kleinridders, André

Journal:

Free Radical Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 57 KB

english, 2018

26

Soybean Oil-Derived Poly-Unsaturated Fatty Acids Enhance Liver Damage in NAFLD Induced by Dietary Cholesterol

Henkel, Janin, Alfine, Eugenia, Saín, Juliana, Jöhrens, Korinna, Weber, Daniela, Castro, José, König, Jeannette, Stuhlmann, Christin, Vahrenbrink, Madita, Jonas, Wenke, Kleinridders, André, Püschel, G

Journal:

Year:

2018

Language:

english

File:

PDF, 4.74 MB

english, 2018

27

Insulin: Schützender Anpassungsmechanismus im Gehirn

Kleinridders, André

Journal:

Diabetologie und Stoffwechsel

Year:

2019

Language:

german

File:

PDF, 104 KB

german, 2019

28

Role for Insulin Signaling in Catecholaminergic Neurons in Control of Energy Homeostasis

A. Christine Könner, Simon Hess, Sulay Tovar, Andrea Mesaros, Carmen Sánchez-Lasheras, Nadine Evers, Linda A.W. Verhagen, Hella S. Brönneke, André Kleinridders, Brigitte Hampel, Peter Kloppenburg, Jen

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

29

Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and InsulinSignaling in Obesity

Ernst, M. B., Wunderlich, C. M., Hess, S., Paehler, M., Mesaros, A., Koralov, S. B., Kleinridders, A., Husch, A., Munzberg, H., Hampel, B., Alber, J., Kloppenburg, P., Bruning, J. C., Wunderlich, F. T

Journal:

Journal of Neuroscience

Year:

2009

Language:

english

File:

PDF, 2.33 MB

english, 2009

30

Editorial: Crosstalk of Mitochondria With Brain Insulin and Leptin Signaling

Kleinridders, André, Ferris, Heather A., Tovar, Sulay

Journal:

Frontiers in Endocrinology

Year:

2018

Language:

english

File:

PDF, 177 KB

english, 2018

31

Molecular effects of dietary fatty acids on brain insulin action and mitochondrial function

Chudoba, Chantal, Wardelmann, Kristina, Kleinridders, André

Journal:

Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 729 KB

english, 2018

32

Insulin Receptor Signaling in Normal and Insulin-Resistant States

Boucher, J., Kleinridders, A., Kahn, C. R.

Journal:

Cold Spring Harbor Perspectives in Biology

Year:

2014

Language:

english

File:

PDF, 1005 KB

english, 2014

33

Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing

Mende, Y., Jakubik, M., Riessland, M., Schoenen, F., Rossbach, K., Kleinridders, A., Kohler, C., Buch, T., Wirth, B.

Journal:

Human Molecular Genetics

Year:

2010

Language:

english

File:

PDF, 562 KB

english, 2010

34

Hepatic Bax Inhibitor-1 Inhibits IRE1 and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance

Bailly-Maitre, B., Belgardt, B. F., Jordan, S. D., Coornaert, B., John von Freyend, M., Kleinridders, A., Mauer, J., Cuddy, M., Kress, C. L., Willmes, D., Essig, M., Hampel, B., Protzer, U., Reed, J.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 4.26 MB

english, 2010

35

PLRG1 Is an Essential Regulator of Cell Proliferation and Apoptosis during Vertebrate Development and Tissue Homeostasis

Kleinridders, A., Pogoda, H.-M., Irlenbusch, S., Smyth, N., Koncz, C., Hammerschmidt, M., Bruning, J. C.

Journal:

Molecular and Cellular Biology

Year:

2009

Language:

english

File:

PDF, 3.04 MB

english, 2009

36

CNS-targets in control of energy and glucose homeostasis

André Kleinridders, A Christine Könner, Jens C Brüning

Journal:

Current Opinion in Pharmacology

Year:

2009

Language:

english

File:

PDF, 441 KB

english, 2009

37

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

Cai, Weikang, Sakaguchi, Masaji, Kleinridders, Andre, Gonzalez-Del Pino, Gonzalo, Dreyfuss, Jonathan M., O’Neill, Brian T., Ramirez, Alfred K., Pan, Hui, Winnay, Jonathon N., Boucher, Jeremie, Eck, Mi

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 5.18 MB

english, 2017

38

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Boucher, Jeremie, Charalambous, Marika, Zarse, Kim, Mori, Marcelo A., Kleinridders, Andre, Ristow, Michael, Ferguson-Smith, Anne C., Kahn, C. Ronald

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

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